SOLALNappi Code: 709278001
We've curated every product in our I DO | Nutrition shop based on their nutrigenomic properties and leading manufacturing standards. Nutrigenomics is the study of food and nutrients as one of the most important environmental modifiers of gene expression. A personalised protocol based on your unique DNA, biochemistry and symptoms can help you create optimal wellness and prevent many chronic lifestyle-related diseases. This is called 'personalised scientific wellness'.
Antioxidant | Blood Sugar | Longevity
Resveratrol is an antioxidant, commonly found in red grapes. It seems to mimic the anti-ageing effects of calorie restriction. Animal studies indicate it decreases the harmful effects of high fat, high-calorie diets. This is probably due to increased fat metabolism by activating the SIRT-1 enzyme. SIRT-1 improves blood sugar metabolism, insulin sensitivity and cell survival.
Pterostilbene is a more potent derivative of resveratrol found in blueberries. Animal studies show that pterostilbene has similar effects to resveratrol but reaches higher levels in the blood and lasts longer in the body.
Grape seed polyphenols are a source of antioxidants for the maintenance of good health.
Benefits | Features
- Trans-resveratrol appears to be the primary active form of resveratrol. Resveratrol has been shown in animal and laboratory studies to exhibit antioxidant effects
- Preliminary research indicates that chronic administration of resveratrol can increase lifespan by activating the SIRT-1 gene and improving heart function.
- Grape seed extract contains phenolic compounds including oligomeric proanthocyanidins (OPC), proanthocyanidins, flavonols and polyflavan-3-ols which have antioxidant activity.
- Pterostilbene is a methylated form of resveratrol which research indicates is better absorbed, metabolised at a slower rate and is pharmacologically more active.
- Packaged in recyclable material
"Resveratrol is a natural antioxidant found in grapes that are believed to enhance the activity of a group of genes called Sirtuins (SIRT-1). These so called ‘longevity genes’ function in protecting and repairing cells thereby enhancing cellular survival. Pterostilbene is a methylated form of resveratrol found in blueberries. Pterostilbene has the following advantages over resveratrol: better absorbed, more active and metabolised slower. The latest research indicates using both forms together is more effective than separately. Grape seed polyphenols are a source of antioxidants for the maintenance of good health".
Pair with these tests
To check if you should include this product in your daily supplement protocol, you can order the following DNA and/or biochemistry tests online:
|Grape seed extract||100mg|
- Adults and children over 12 years of age: Take 1 capsule twice daily.
- Children 7-12 years of age: Take 1 capsule daily.
- Take with or shortly after meals.
Cautions | Warnings | Interactions
Consult your healthcare practitioner before use. Do not exceed recommended dosages unless on the advice of a health care provider. If you are on medication, taking nutritional supplements, suffering from any medical condition, pregnant, or breastfeeding, it is advisable to seek medical advice before starting any new food, supplement or remedy. Do not use this product if you are allergic to any of the ingredients. Keep out of the reach of children.
Do not exceed recommended dosages unless on the advice of a health care provider. Do not use this product if you are allergic to any of the ingredients. If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy. Safety in children has not been established.
Side effects may include dizziness, skin rash, gastrointestinal upset and headache.
Warfarin and anticoagulants: Use cautiously in patients taking anticoagulants such as warfarin, aspirin, nonsteroidal anti-inflammatory or antiplatelet agents, as OPCs may alter platelet function and aggregation Monoamine oxidase inhibitors (MAOI’s): Resveratrol competitively inhibits monoamine oxidase A and thus should be used with caution in individuals using monoamine oxidase inhibitors (MAOI’s). Cytochrome P450 3A4: Resveratrol might inhibit the cytochrome P450 3A4 enzymes and thereby increase the levels of the caffeine, chlordiazepoxide, clomipramine, clopidogrel, clozapine, diazepam, estradiol, flutamide, fluvoxamine, haloperidol, imipramine, mexiletine, mirtazapine, naproxen, nortriptyline , olanzapine, ondansetron, propafenone , propranolol, ropinirole, theophylline, verapamil, warfarin, lovastatin, ketoconazole, itraconazole, fexofenadine, triazolam, use with caution. Methotrexate: Use cautiously in individuals on methotrexate therapy due to a theoretical risk of increased methotrexate toxicity via inhibition of xanthine oxidase. ACE inhibitors: Use with caution with ACE inhibitors as can inhibit angiotensin-1 converting enzyme activity by noncompetitive inhibition.
Hormone sensitive conditions: Since resveratrol may have estrogenic effects, women with hormone sensitive conditions should avoid resveratrol. Some of these conditions include breast, uterine, ovarian cancer, and endometriosis and uterine fibroids. Surgery: Discontinue use at least two weeks prior to surgery or dental procedures, due to the altered platelet function and aggregation effects.
Pregnancy | Breast Feeding
Safety in pregnancy and breastfeeding has not been established.
Store tightly closed in a cool, dry, dark place.