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GUT | Comprehensive Stool Analysis


R 7,850.00

"JOINCIRCLES enables you to own your own medical data. When you receive your biochemistry results, we strongly advise that you contact one or more of healthcare practitioners listed under our "Practitioner Circle' who have been trained to interpret these tests. Once you have a plan from your practitioner, you can come back and shop your personalised daily nutrition, environment and lifestyle choices. As the medical director, I'm available to help you chose the right test and/or practitioner for your needs". Dr Heidi

Gastrointestinal complaints are among the most common in medical care. Symptoms associated with GI disorders include persistent diarrhoea, constipation, bloating, indigestion, irritable bowel syndrome and malabsorption. This comprehensive profile helps pinpoint the causes of gastrointestinal symptoms and chronic systemic conditions.

The Comprehensive Stool Analysis can help assess digestive and absorptive functions, the presence of opportunistic pathogens, and to monitor the efficacy of therapeutic treatment of gut disorders. 

This non-invasive diagnostic assessment* enables you to evaluate the status and levels of intestinal beneficial, commensal, and pathogenic bacteria and yeast/fungus. It also measures key markers of digestion, absorption and gut (digestive tract) inflammation. Knowing this info helps you and your doctor choose the best pharmaceutical or natural treatment for your symptoms. 

*The Comprehensive Stool Analysis does not include analysis for parasites. For assessment of the presence of parasites, consider the Comprehensive Stool Analysis with Parasitology test

More info

Cornerstones of good health include proper digestion of food, assimilation of nutrients, exclusion of pathogens and timely elimination of waste. To obtain benefits from food that is consumed, nutrients must be appropriately digested and then efficiently absorbed into portal circulation.

Microbes, larger-sized particles of fibre, and undigested foodstuffs should remain within the intestinal lumen. Poor digestion and malabsorption of vital nutrients can contribute to degenerative diseases, compromised immune status and nutritional deficiencies. Impairment of the highly specific nutrient uptake processes, or compromised GI barrier function, as in "leaky gut syndrome," can result from a number of causes including:

  • Low gastric acid production
  • Chronic maldigestion
  • Food allergen impact on bowel absorptive surfaces
  • Bacterial overgrowth or imbalances (dysbiosis)
  • Pathogenic bacteria, yeast or parasites and related toxic irritants
  • The use of NSAIDs and antibiotics

Impairment of intestinal functions can contribute to the development of food allergies, systemic illnesses, autoimmune disease, and toxic overload from substances that are usually kept in the confines of the bowel for elimination.

Efficient treatment of gut dysfunctions incorporates a comprehensive guided approach that should include consideration of elimination of pathogens and exposure to irritants, supplementation of hydrochloric acid, pancreatic enzymes and pre- and probiotics, and repair of the mucosal barrier. Please search our 'GUT Shop' for more info.

    Benefits | Features

    • Identifies* pathogenic gut bacteria and yeast/fungi
    • This test determines which antimicrobial agent (treatment) susceptibility testing to pharmaceutical and natural agents is also performed for appropriate bacterial and fungal species. This allows you and your doctor to determine the best pharmaceutical or natural treatment for you.
    • By measuring your faecal levels of elastase (which shows pancreatic exocrine sufficiency), fat, muscle and vegetable fibres, and carbohydrates, important information can be gleaned regarding the efficiency of your digestion and nutrient absorption.
    • Inflammation can significantly increase intestinal permeability (leaky gut) and compromise the absorption of nutrients from the food you eat. The extent of inflammation, whether caused by pathogens or inflammatory bowel disease (IBD), can be assessed and monitored by measuring the levels of biomarkers such as lysozyme, lactoferrin, white blood cells and mucus in your stool. These markers can be used to differentiate between inflammation associated with potentially life-threatening inflammatory bowel disease (IBD), which requires lifelong treatment, and less severe inflammation that can be associated with irritable bowel syndrome (IBS) which is frequently due to the presence of enteroinvasive pathogens (pathogens that produce disease in the intestinal tract).
    • Using growth-based culture, the standard of practice in clinical microbiology, as well as sensitive biochemical assays and microscopy, this thorough profile thoroughly evaluates the status of beneficial and pathogenic microorganisms including aerobic and anaerobic bacteria, yeast and parasites.
    • *Please note: The Comprehensive Stool Analysis does not include analysis for parasites. If you would like to include the assessment for intestinal parasites, please consider our Comprehensive Stool Analysis with Parasitology test

    Tests for

    • Intestinal bacteria: beneficial bacteria, imbalances in commensal bacteria, and pathogenic bacteria
    • Intestinal fungi/yeasts
    • Undigested food in various forms
    • Biomarkers for intestinal inflammation, IBD, IBS
    • Blood: old (this could mean there is bleeding higher up in the intestines) and fresh blood
    • Immune cells
    • Faecal pH

    Who would benefit from this test?

    Anyone with 1 or more of the following symptoms or conditions:

    • Gastrointestinal symptoms
    • Autoimmune disease
    • Joint pain
    • IBD (inflammatory bowel disease)/IBS (irritable bowel syndrome)
    • Inflammation
    • Food sensitivities
    • Nutritional deficiencies
    • Skin conditions (atopic dermatitis)

    Contributing | Causal factors

    • Bacterial overgrowth or imbalances (dysbiosis)
    • Chronic maldigestion
    • The effect of food allergens on bowel absorptive surfaces
    • Low gastric acid production
    • Pathogenic bacteria, yeast or parasites and related toxic irritants
    • The use of NSAIDs and antibiotics

        Pair with these DNA Tests

        Order these DNA tests to find out more about your unique genetics variations:


        Test analytes

        Acetate; stool
        Additional pathogens culture; stool
        Bacteriology^ culture, aerobic; stool
        Butyrate; stool
        Calprotectin; stool
        Carbohydrates; stool
        Elastase; stool
        Fat Stain; stool
        Lactoferrin*; stool
        Lysozyme; stool
        Mucous; stool
        Muscle Fibers; stool
        Occult Blood; stool
        Propionate; stool
        Red Blood Cells; stool
        Valerate; stool
        Vegetable Fibers; stool
        White Blood Cells; stool
        Yeast^^ culture; stool
        ph; stool
        sIgA**; stool

        *Lactoferrin is only markedly elevated prior to and during the active phases of IBD (inflammatory bowel disease), but not with IBS (irritable bowel syndrome). Monitoring faecal lactoferrin levels in patients with IBD can, therefore, facilitate timely treatment of IBD, and the test can be ordered separately.

        **Since the vast majority of secretory IgA (sIgA) is normally present in the GI tract, where it prevents binding of pathogens and antigens to the mucosal membrane, it is essential to know the status of sIgA in the gut. sIgA is the only bona fide marker of humoral immune status in the GI tract. 


        ^Possible Bacteria Identification List

        ^^Possible Yeast Identification List

        Test sample report

        Test sample type

        • Stool sample: One fresh stool sample in a small sample bottle.

        Processing time

        About 2 weeks

        Lab's name for test

        Comprehensive Stool Analysis 

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