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Energising Adaptogens™


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We've curated every product in our I DO | Nutrition shop based on their nutrigenomic properties and leading manufacturing standards. Nutrigenomics is the study of food and nutrients as one of the most important environmental modifiers of gene expression. A personalised protocol based on your unique DNA, biochemistry and symptoms can help you create optimal wellness and prevent many chronic lifestyle-related diseases. This is called 'personalised scientific wellness'.


Adaptogens are pure herbal extracts that invigorate during times of stress and fatigue. They also safely enhance physical performance and exercise ability. There are two groups of adaptogens: primary adaptogens are responsible for the health benefits, whilst secondary adaptogens enhance the effectiveness of the primary adaptogens. Energising Adaptogens™ contains all primary and secondary adaptogens.

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Pharmacological Action

Rhodiola contains rhodioloside which is attributed to its adaptogenic effects. Rhodiola enhances the body’s tolerance to stress by influencing key brain chemicals, such as serotonin and norepinephrine, and feel-good opioids such as beta-endorphins. Rhodiola has also demonstrated the ability to improve memory and cognitive function under stressful conditions. Eleutherococcus senticosus is thought to stimulate the pituitary-adrenal cortex system. Schizandra is used as an adaptogen for increasing resistance to disease and stress, increasing energy and is hepatoprotective by increasing glutathione. Reishi has the unique ability among medical mushrooms to calm and support nerve function for people with chronic stress, anxiety, or insomnia. Astragalus is often used in the treatment of chronic fatigue syndrome and has positive effects on the immune system, liver, and cardiovascular system. Preliminary research indicates that ashwagandha suppresses stress-induced increases of dopamine receptors in the corpus striatum of the brain. It also appears to reduce stress-induced increases of plasma corticosterone, blood urea nitrogen, and blood lactic acid. Ashwagandha seems to have anxiolytic effects, possibly by acting as a gamma-aminobutyric acid (GABA) mimetic agent. In vitro evidence suggests that gotu kola might bind cholecystokinin (CCK) and GABA receptors, which might be responsible for reported anxiolytic effects of gotu kola. Liquorice appears to compliment Korean ginseng by increasing serum cortisol concentrations. Codonopsis seems to be able to stimulate the central nervous system. It seems to increase endurance and has adrenergic-blocking properties.

Product Composition

Rhodiola extract






Schizandra extract 10%


Reishi mushroom extract


Panax ginseng extract


Astragalus extract 70%


Ashwagandha KSM 66


Gotu kola extract 4:1


Liquorice aquasol


Codonopsis Extract 5:1


Inactive ingredients: Silicon dioxide, hypromellose (cellulose) vegetarian capsule shell (gelatine free), magnesium silicate, magnesium stearate (vegetarian – flow agent), microcrystalline cellulose and silicon dioxide.

Suitable for vegans and vegetarians.



For mental energy and to neutralise fatigue:
Under 80 kg body weight: 1 capsule twice daily.
Over 80 kg body weight: 2 capsules twice daily.

To enhance exercise performance:

Under 80 kg body weight: 2 capsules 15 minutes before exercise.

Over 80 kg body weight: 3 – 4 capsules 15 minutes before exercise.

Product Warnings

Do not exceed recommended dosages unless on the advice of a healthcare
practitioner. Do not use this product if you are hypersensitive (allergic) to any of the ingredients. If you are on any medication or suffering from any medical
condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy. This medicine has not been evaluated by the Medicines Control Council. This medicine is not intended to diagnose, treat, cure or prevent any disease.

Special Precautions

Stomach Acidity: May cause stomach acidity if taken on an empty stomach.
Hormone sensitive cancers/conditions: Preliminary evidence shows that Korean ginseng may have oestrogenic effects. Women with hormone conditions such as breast cancer, uterine cancer, ovarian cancer, endometriosis and uterine fibroids should avoid Energising Adaptogens™.
Diabetes: Energising Adaptogens™ could have hypoglycaemic effects. Use in diabetics might increase the risks of hypoglycaemic episodes.
Hypertension: The mineralocorticoid effects of liquorice can increase blood pressure.

Side Effects

Reported side effects include dizziness, dry mouth, insomnia, decreased appetite, diarrhoea, headache, vertigo, skin rash, palpitations, irritability, mastalgia, uterine bleeding, hypertension, slight drowsiness, heartburn, nosebleeds, acid indigestion and stomach pain.


There are no known contraindications.


  • Alcohol: Concomitant use with eleutherococcus senticosus, may enhance the sedative effects of alcohol and Korean ginseng significantly increases the metabolism of alcohol.
  • Warfarin and anticoagulant medicines: Energising Adaptogens™ appears to affect the anticoagulant and antiplatelet effects and should only be used under the supervision of a medical practitioner.
  • Antidiabetic medicines: Energising Adaptogens™ seems to have hypoglycaemic activity. Monitor glucose levels closely. Some antidiabetic medicines include glimepiride, glyburide, insulin, pioglitazone, rosiglitazone and others.
  • Antihypertensive medicines: Theoretically, liquorice might reduce the effect of antihypertensive medicines.
  • Digoxin: One case report associated Siberian ginseng intake with elevated serum digoxin levels, although there were no symptoms of toxicity. It is not clear whether this was due to a pharmacokinetic interaction which increased serum digoxin levels, or due to interference with the digoxin assay.
  • Lithium: Energising Adaptogens™ is thought to have diuretic properties. Theoretically due to these potential diuretic effects, lithium excretion may be reduced and lead to increased levels. Liquorice might increase the risk of lithium toxicity due to potassium loss.
  • Tacrolimus: Schizandra increases the absorption and plasma levels of tacrolimus.
  • Antihypertensive medicines: Reishi mushroom may have antihypertensive effects and may enhance the effects of antihypertensive medicines.
  • Caffeine: Theoretically, caffeine might have an additive effect on the stimulant effects of Korean ginseng.
  • Furosemide: There is some concern that Korean ginseng may contribute to diuretic resistance. Use this combination with caution.
  • Immunosuppressants: Theoretically, concurrent use may interfere with immunosuppressants by increasing the immune system.
  • Monoamine oxidase inhibitors (MAOI): Panax ginseng can interfere with MAOI therapy.
  • Benzodiazepines and CNS depressants: Energising Adaptogens™ might have additive effects when used with benzodiazepines and other CNS depressants.
  • Hepatotoxicity: There is some concern that gotu kola might cause hepatotoxicity in some individuals. Theoretically concomitant use with other hepatotoxic medicines might increase the risk of developing liver damage.
  • Corticosteroids: Theoretically, concomitant use might potentiate the duration of activity of corticosteroids.

Pregnancy and Breastfeeding

Safety during pregnancy and breastfeeding has not been established.

Storage Instructions

Store in a cool dry place below 25°C. Keep out of the reach of children.

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