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Premenstrual syndrome (PMS) is one of the major health issues for childbearing-age women, as both physical and psychological symptoms can affect health and quality of life. Epidemiological studies show that 75% of fertile women have mild to moderate symptoms of PMS; 3-8% may present severe symptoms. Hormonal dysfunction can impact mood, sleep, and appetite and lead to symptoms such as anxiety, pain, hot flashes, and even memory impairment. 

“There’s no ‘one’ hormone involved in PMS—this is a complex dance and interaction between hormones,” says Functional Medicine Educator Margaret Christensen, MD. “What we want to do from a functional standpoint is to address the actual underlying hormonal imbalances and triggers. Is it high-stress hormones? That’s one of the number one contributors to PMS, and it is lack of things like sleep, lack of adequate nutrients like B vitamins and magnesium, which are critically important in hormonal balancing pathways.”

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