We've curated every product in our I DO | Nutrition shop based on their nutrigenomic properties and leading manufacturing standards. Nutrigenomics is the study of food and nutrients as one of the most important environmental modifiers of gene expression. A personalised protocol based on your unique DNA, biochemistry and symptoms can help you create optimal wellness and prevent many chronic lifestyle-related diseases. This is called 'personalised scientific wellness'.
Stimulates adrenal function for use in exhaustion and adrenal burnout. Years of stress can exhaust the adrenal glands which the body relies on to manufacture the stress-coping and anti-fatigue hormone, cortisol. The adrenals also produce aldosterone, essential for water/mineral balance, as well as pregnenolone and DHEA, the building blocks of estrogen, progesterone and testosterone. Burnout is indicated for people who are suffering from adrenal exhaustion from years of exposure to stress and works by boosting excessively low levels of cortisol. Adrenal fatigue is characterised by tiredness and chronic fatigue, coupled with some of the following symptoms: chronic pain, mild depression, anxiety, reduced stress-coping ability, patchy hair loss, insomnia, poor blood sugar control (up or down), weight gain, frequent infections, reduced sex drive, a craving for fatty, salty or high-protein foods, difficulty getting up in the morning, worsening of allergies, reduced memory and focus, alternating diarrhoea and constipation, and indigestion. Burnout contains concentrated herbal extracts for enhanced effectiveness, not herb powder and has synergistic dual action: stimulating adrenal function and reducing adrenal hormone breakdown.
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Adrenal fatigue occurs when the adrenal glands, situated above the kidneys, become overworked or damaged, usually from long-term exposure to stress. As a result of being overworked, they secrete reduced amounts of the adrenal hormones, the main ones being cortisol, aldosterone, pregnenolone, DHEA and adrenaline. The most important of these is cortisol, because when this is lowered, the body will no longer be able to deal with stress, a situation which can lead to chronic fatigue syndrome.
Korean ginseng is an adaptogen that enhances energy and improves adrenal function. The term adaptogen refers to Korean ginseng’s buffering ability; to stimulate an underactive adrenal gland by affecting the hypothalamic pituitary adrenal (HPA) axis, by slowing down an overactive adrenal, thereby reducing the effects of stress. Korean ginseng also protects nerve function and enhances memory and coping ability during times of stress. Korean ginseng will also help treat the blood-sugar irregularities and low blood pressure that occur with under-active adrenal glands.
Liquorice slows down the breakdown of cortisol in the body by inhibiting renal 11 beta-hydroxysteroid dehydrogenase, reducing the conversion of cortisol to inactive cortisone in the kidneys, allowing the adrenals time to recuperate. Liquorice also helps protect from the acidic indigestion sometimes associated with adrenal fatigue and burnout. Echinacea is a potent adrenal stimulant, and also helps fight infections (such as candida) that commonly occur with adrenal fatigue. Echinacea achieves this by increasing phagocytosis and increasing lymphocyte activity, possibly by promoting the release of tumour necrosis factor (TNF), interleukin-1 (IL-1), and interferon. Several constituents of Echinacea seem to be involved in stimulating this nonspecific immune response.
Chromium polynicotinate helps prevent the blood sugar irregularities and fatigue caused by an underactive adrenal gland as it is a vital component of glucose tolerance factor (GTF). Clinical evidence shows that vitamin B1 (thiamine pyrophosphate) counters the adrenal insufficiency that occurs from trauma such as surgery. Vitamin B5 (calcium-d-pantothenate) in the form of coenzyme A is closely involved in adrenal cortex function and has come to be known as the anti-stress vitamin; it acts as an enzyme to facilitate the production of all adrenal anti-stress hormones.
Each capsule contains the following active ingredients:
|Panax ginseng (Korean) 5:1 extract||100mg|
|Liquorice 6:1 extract||250mg|
|Chromium polynicotinate (12.4% chromium)||100µg|
|Vitamin B1 (thiamine pyrophosphate)||3.1mg|
|Vitamin B5 (calcium-d-pantothenate)||25mg|
Inactive ingredients: Hypromellose (cellulose) vegetarian capsule shell (gelatine free), microcrystalline cellulose, magnesium stearate (vegetarian – flow agent), magnesium silicate, silicon dioxide and colloidal silicon dioxide.
Contains plant extracts and natural fillers, with no colourants added – therefore the colour of the capsule contents may vary slightly from batch to batch.
Suitable for vegans and vegetarians.
Take 1 capsule every 6-8 hours when needed. Do not exceed 3 capsules in a 24 hour period.
Do not use this product if you are hypersensitive (allergic) to any of the ingredients. If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy. Do not exceed recommended dosages unless on the advice of a healthcare practitioner. This medicine has not been evaluated by the Medicines Control Council. This medicine is not intended to
diagnose, treat, cure or prevent any disease.
Burnout™ is generally well tolerated, but the following side effects may be experienced: insomnia, diarrhoea, vomiting, headache, heartburn, allergy, constipation and less commonly individuals can experience mastalgia, vaginal bleeding, amenorrhea, tachycardia, palpitations, hypertension, hypotension, oedema, decreased appetite, hyperpyrexia, pruritus, rose spots, headache,
vertigo, euphoria and mania.
Anticoagulant/antiplatelet medication: Liquorice seems to increase the metabolism and decrease levels of warfarin. Individuals taking warfarin should avoid liquorice.
- Anticoagulant/antiplatelet medication: Liquorice seems to increase the metabolism and decrease levels of warfarin. Individuals taking warfarin should avoid Burnout™.
- Alcohol: Significantly increases the clearance of alcohol.
- Antidiabetic medication: May enhance the blood glucose lowering effects, use with caution.
- Caffeine: Theoretically caffeine may have an additive effect to the stimulant effects of Panax ginseng.
- Cytochrome P450 2D6, P450 2C9, P 450 3A4 and P450 2B6: There is some evidence that Panax ginseng and liquorice can inhibit these cytochromes.
- Caution should be exercised when using medication metabolised by this enzyme. Some of these medications include: amitriptyline, clozapine, codeine, desipramine, donepezil, fentanyl, flecainide, fluoxetine, meperidine, methadone, meto¬prolol, olanzapine, ondansetron, tramadol, trazodone, ketamine, phenobarbital, orphenadrine, secobarbital, dexamethasone, celecoxib, diclofenac, fluvastatin, ibuprofen, losartan, phenytoin, piroxicam, tamoxifen, tolbutamide, torsemide, warfarin, lovastatin, clarithromycin, cyclosporine, diltiazem, oestrogens, indinavir, triazolam and others.
- Antihypertensive medication: Liquorice increases blood pressure in a dose-dependent manner.
- Digoxin: Overuse and misuse of liquorice with cardiac glycoside therapy might increase the risk of cardiac toxicity due to potassium loss.
- Cortisone: Use of cortisone with this product could cause excessive potassium depletion and require potassium supplementation, speak to your medical practitioner.
Pregnancy and Breastfeeding
Safety during pregnancy and whilst breastfeeding has not been established.
Store in a cool dry place below 25°C, protect from light. Keep out of reach of children.