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IL-6 gene (Interleukin 6) encodes the pro-inflammatory protein that plays a crucial role in inflammation and regulates expression of a C-reactive protein (CRP): A plasma protein that rises in the blood with the inflammation from certain conditions.
C-reactive protein (CRP) is one of the plasma proteins known as acute-phase proteins: proteins whose plasma concentrations increase (or decrease) by 25% or more during inflammatory conditions such as a sore throat, injured leg or a sudden allergy.
How amazing are our bodies?
The problem is when this signalling goes a bit awry and low-grade, chronic inflammation sets in.
Chronic inflammation is associated with obesity and visceral fat deposition, insulin resistance, dyslipidaemia and increased risk for cardiovascular disease.
If you have a medium to high impact variation in this gene, it may mean that the regulation of the proteins involved in the pro-inflammatory 'off and on' signally does not work optimally.
You may wish to 'add in' some of the NUTRITION, ENVIRONMENT & LIFESTYLE choices that can provide optimal support to this genetic pathway.