This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. This protein regulates the development of numerous tissue and cell types, including cartilage, joints, brown fat (the good fat!), teeth, and the growth of neuronal axons and dendrites.
Variations in this gene are associated with an increase in injury susceptibility and osteoarthritis.
If you have a medium to high impact genetic variation in this gene, shop here for products that aim to provide optimal support to its biochemical pathway.