Shop here for nutrigenomic products that provide targeted nutrition to support this genetic pathway. This gene plays a protective role in the body. Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. Nitric oxide is synthesized from L-arginine by nitric oxide synthases. Variations in this gene are associated with susceptibility to coronary spasm.
The T allele genetic variation affects the enzyme thereby reducing nitric oxide bioavailability in the blood vessel wall and promoting atherosclerosis, as a result, it is associated with atherosclerosis, essential hypertension, end-stage renal disease, and pre-eclampsia. Ensure adequate antioxidant and omega 3 fatty acids intake.
If you have a medium to high impact genetic variation on this gene it's a good idea to 'add in' antioxidant choices list here.