Want to be healthier?
It starts by personalising your nutrition, environment and lifestyle choices from your DNA up.
Having more information about your unique DNA and it's variations will enable you to start personalising your nutrition, environment and lifestyle choices. Personalisation also helps you focus your health budget so you only pay for things your body really needs.
This month's featured gene is MC4R.
The major driving force behind obesity in modern society is overeating, which is largely coded in genes that are responsible for appetite and satiety regulation. Appetite is the desire to eat while satiety refers to the sensation of fullness after eating. MC4R is one of these genes.
Mutations in MC4R are the most common genetic cause of obesity. Many MC4R mutations have been documented. Some reduce gene function, some eliminate function altogether. While these mutations account for about 6-8% severe inheritable obese symptoms, they are relatively rare in general population.
One common variant of the MC4R gene, carried by 22% of the general population, causes reduced MC4R protein level in the hypothalamus of the brain. Carriers of this variant have both increased appetite and decreased satiety. They tend to eat larger amounts of food, snack more frequently and like to eat fatty foods (ref: GB Health Watch).
Having information about your unique genetic variation for this gene will empower you to make better choices to support it.
To become healthier, we believe that we should all stand at the centre of our health choices, and own and know our own medical data. That's why we sell DNA and advanced biochemistry home tests in our shop, as well as nutrition, environment and lifestyle products that can feed, protect and nurture your DNA. You can start personalising your health choices from your DNA up or just dive straight in and start shopping better choices now. We're here to help if you have any questions.
A healthy balance starts here!
Did you know that being overweight is a risk factor for many lifestyle-related chronic diseases such as cardiovascular disease, diabetes type 2 and many types of cancers.
Your genes are not your destiny! Research is showing that, by changing what you expose your DNA to, you can change the way your DNA expresses itself! You can literally 'turn off' your potential for lifestyle-related chronic diseases or 'turn on' optimal wellness.
“I love the work JOINCIRCLES does in personalising my recommendations.
As a triathlete and active sport person with a media company and three kids, I have to take care to balance my health and diet, and this can be a confusing and tricky process. Stress, depleted energy levels, bad and convenient nutrition, all these things have a negative effect and in my experience, have resulted in burnout and painful injury. JOINCIRCLES has made supplementing healthy decisions convenient and easy".
Dear Heidi, I just wanted to let you know its been two years since my cancer diagnosis. I was looking back over the dreadful journey and you were just outstanding! Your support, knowledge and interest and caring were just what I needed. I have no words to thank you for all the love and time and care you put in to me. You made a difference in my life. I want you to know that. I am immensely grateful. Your advice has become my bible and I live by it. Every single day.
THANK YOU. You are my angel.
Lots of love
"I was fortunate to discover the JOINCIRCLES while they were assisting my mother with her cancer recovery.
My mom’s brush with cancer made me determined to make better health and lifestyle choices for myself, and my daughter too. I met Dr Heidi van Loggerenberg and was amazed at her wealth of cutting-edge health knowledge. Margie gave me fantastic advice on non-toxic, green makeup and skincare, and I haven’t looked back since.
“A big thank you for being with me on my journey to optimal health!
I just wanted to say how awesome it is to have access to the products you are offering, all in one place and easy, efficient, fast online service. Not only have I been educated as to the benefits of making healthy choices, but also the dangers of not being careful of what I'm putting on and in my body. I love that I'm making personalised choices on my way to optimal health!".
“JOINCIRCLES takes the guess work out of choosing healthy products!
I’m the youngest of three siblings. My sister, mom, and aunt have all had breast cancer so prevention is foremost in my mind for myself and my family. JOINCIRCLES has made prevention easy! JOINCIRCLES's service is quick and Dr. Heidi and Margie are always an email or call away to offer personalised help. I love receiving my optimal wellness ‘ToolKits’ – they are jam packed with super healthy items and delivered directly to my door by courier!”.
For years I looked for answers so that I could proactively manage my health.
JOINCIRLCES gave me the answer. By understanding my own unique DNA, my real-time biomarkers and getting the support that I need to make the right choices on a daily basis, the results have been quick and amazing! I feel better than ever.
While taking the tests was an investment, it was the best investment I have ever made. I can refer to my DNA tests for the rest of my life and I will do my biochemistry tests on an annual basis to measure and track my progress. The most important and personal for me, is that I don’t feel like a ticking time bomb for Alzheimer’s, the horrible illness that has drastically affected my mother.
A great place to start is always with more knowledge. Find out more about what's possible in the personalised approach to well-being. 'Epigenetics' is a fast emerging science that carries much optimism that we can all chose to play a part in the creation of our lifestyle-related diseases or optimal wellness.
We see 'wellness' as personalised, scientific and integrated. JOINCIRCLES enables you and your healthcare practitioners to take the 'guesswork' out of being optimally well.
Nutrition is one of the most important and controllable 'circles' that you can join around your DNA daily. Now, a 'good diet' is a 'personalised' one. Many of our supplements in our shop are based on nutrigenomic principles and support specific biochemical pathways that are tested for in our DNA tests.
Your 'environment' refers to everything that your body and cells are exposed to - chemicals in our body care, home and garden products, fabrics, toys, food, water and the air we breathe! Many of these bad chemicals can change the way our DNA expresses itself and can 'turn on' lifestyle-related chronic diseases.
In our shop, you can shop with peace of mind. All our products are free from xenoestrogens, endocrine disruptors, DNA mutators and carcinogens.
Protect your DNA daily.
In short, your lifestyle is how you choose to live your life. Making the right lifestyle choices and creating the right habits is a critical part of optimal health.
We see many cancers as lifestyle-related chronic diseases. New research shows that exercise can reduce our cancer risk by 30-50% - that's HUGE!!
Lifestyle is another key 'circle' that you can join around your DNA daily to create optimal wellness.